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Accepted for/Published in: JMIR mHealth and uHealth

Date Submitted: Apr 6, 2020
Date Accepted: Sep 7, 2020

The final, peer-reviewed published version of this preprint can be found here:

Opportunities for Mobile App–Based Adherence Support for Children With Tuberculosis in South Africa

Morse RM, Myburgh H, Reubi D, Archey AE, Busakwe L, Garcia-Prats AJ, Hesseling AC, Jacobs S, Mbaba S, Meyerson K, Seddon JA, van der Zalm MM, Wademan DT, Hoddinott G

Opportunities for Mobile App–Based Adherence Support for Children With Tuberculosis in South Africa

JMIR Mhealth Uhealth 2020;8(11):e19154

DOI: 10.2196/19154

PMID: 33174850

PMCID: 7688382

Opportunities for Mobile App–Based Adherence Support for Child Tuberculosis in South Africa: Viewpoint

  • Rachel M Morse; 
  • Hanlie Myburgh; 
  • David Reubi; 
  • Ava E Archey; 
  • Leletu Busakwe; 
  • Anthony J Garcia-Prats; 
  • Anneke C Hesseling; 
  • Stephanie Jacobs; 
  • Sharon Mbaba; 
  • Kyla Meyerson; 
  • James A Seddon; 
  • Marieke M van der Zalm; 
  • Dillon T Wademan; 
  • Graeme Hoddinott

ABSTRACT

Tuberculosis (TB) is the number one infectious cause of death globally. Young children, generally under the age of five years, are at highest risk of progressing from TB infection to TB disease and of developing the most severe forms of TB. Most current TB drug formulations have poor acceptability among children and require consistent adherence for prolonged periods of time. These challenges complicate children’s adherence to treatment and caregivers’ daily administration of the drugs. Rapid developments in mobile technologies and apps present opportunities for using widely available technology to support national TB programs and patient treatment adherence. Pilot studies have demonstrated that mobile apps are a feasible and acceptable means of enhancing children’s treatment adherence for other chronic conditions. Despite this, no mobile apps have been developed for children that aim to promote adherence to TB treatment. In this paper we draw on our experiences of researching in clinical pediatric TB studies in South Africa. We present hypothetical scenarios of children’s adherence to TB medication to suggest priorities for how a mobile–based app that incorporates behavioral and educational strategies could address some of the adherence support gaps faced by children diagnosed with TB. We argue that a mobile–based app has the potential to lessen some of the negative experiences that children associate with taking TB treatment and to facilitate a more positive treatment adherence experience for children and their caregivers.


 Citation

Please cite as:

Morse RM, Myburgh H, Reubi D, Archey AE, Busakwe L, Garcia-Prats AJ, Hesseling AC, Jacobs S, Mbaba S, Meyerson K, Seddon JA, van der Zalm MM, Wademan DT, Hoddinott G

Opportunities for Mobile App–Based Adherence Support for Children With Tuberculosis in South Africa

JMIR Mhealth Uhealth 2020;8(11):e19154

DOI: 10.2196/19154

PMID: 33174850

PMCID: 7688382

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