Maintenance Notice

Due to necessary scheduled maintenance, the JMIR Publications website will be unavailable from Wednesday, July 01, 2020 at 8:00 PM to 10:00 PM EST. We apologize in advance for any inconvenience this may cause you.

Who will be affected?

Accepted for/Published in: JMIR Medical Informatics

Date Submitted: Apr 16, 2019
Date Accepted: Jul 19, 2019

The final, peer-reviewed published version of this preprint can be found here:

Characterizing Artificial Intelligence Applications in Cancer Research: A Latent Dirichlet Allocation Analysis

Tran BX, Latkin CA, Sharafeldin N, Nguyen K, Vu GT, Tam WW, Cheung NM, Nguyen HLT, Ho CS, Ho RC

Characterizing Artificial Intelligence Applications in Cancer Research: A Latent Dirichlet Allocation Analysis

JMIR Med Inform 2019;7(4):e14401

DOI: 10.2196/14401

PMID: 31573929

PMCID: 6774235

Characterizing Artificial Intelligence Applications in Cancer Research using Latent Dirichlet Allocation

  • Bach Xuan Tran; 
  • Carl A. Latkin; 
  • Noha Sharafeldin; 
  • Katherina Nguyen; 
  • Giang Thu Vu; 
  • Wilson W.S. Tam; 
  • Ngai-Man Cheung; 
  • Huong Lan Thi Nguyen; 
  • Cyrus S.H. Ho; 
  • Roger C.M. Ho

ABSTRACT

Background:

Artificial Intelligence (AI) - based therapeutics, devices and systems are vital innovations in cancer control.

Objective:

This study analyzes the global trends, patterns, and development of interdisciplinary landscapes in AI and cancer research.

Methods:

Exploratory factor analysis was applied to identify research domains emerging from contents of the abstracts. Jaccard’s similarity index was utilized to identify terms most frequently co-occurring with each other. Latent Dirichlet Allocation was used for classifying papers into corresponding topics.

Results:

The number of studies applying AI to cancer during 1991-2018 has been grown with 3,555 papers covering therapeutics, capacities, and factors associated with outcomes. Topics with the highest volumes of publications include 1) Machine learning, 2) Comparative Effectiveness Evaluation of AI-assisted medical therapies, 3) AI-based Prediction. Noticeably, this classification has revealed topics examining the incremental effectiveness of AI applications, the quality of life and functioning of patients receiving these innovations. The growing research productivity and expansion of multidisciplinary approaches, largely driven by machine learning, artificial neutral network, and artificial intelligence in various clinical practices.

Conclusions:

The research landscapes show that the development of AI in cancer is focused not only on improving prediction in cancer screening and AI-assisted therapeutics, but also other corresponding areas such as Precision and Personalized Medicine and patient-reported outcomes.


 Citation

Please cite as:

Tran BX, Latkin CA, Sharafeldin N, Nguyen K, Vu GT, Tam WW, Cheung NM, Nguyen HLT, Ho CS, Ho RC

Characterizing Artificial Intelligence Applications in Cancer Research: A Latent Dirichlet Allocation Analysis

JMIR Med Inform 2019;7(4):e14401

DOI: 10.2196/14401

PMID: 31573929

PMCID: 6774235

The author of this paper has made a PDF available, but requires the user to login, or create an account.

© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.