JMIR Publications

ABSTRACT

Background:

Dementia is the leading cause of disability worldwide and interventions aimed at reducing the prevalence and burden of the disease are urgently needed. Maintain Your Brain (MYB) is a randomized controlled trial of a multi-modal digital health intervention targeting modifiable dementia risk factors for the main objective of combating cognitive decline and potentially preventing dementia. In addition to behavioural modules targeting mood, nutrition, and physical exercise, a new Brain Training System (BTS) will deliver computerised cognitive training (CCT) throughout the trial for the purpose of providing systematic, challenging and personally adaptive cognitive activity.

Objective:

To describe the design and development of BTS.

Methods:

BTS has been designed with a central focus on the end user. Raw training content is provided by our partner NeuroNation and delivered in several innovative ways. A baseline cognitive profile directs selection and sequencing of exercises within and between sessions, and is updated during the 10-week 30-session module. Online trainers are available to provide supervision at different levels of engagement, including face-to-face share-screen coaching, a key implementation resource that is triaged by a ‘red flag’ system for automatic tracking of user adherence and engagement, or by user-initiated help requests. Individualised and comparative feedback is provided to aid motivation, as well as for the first time, establishment of a social support network for the user based on their real-world circle of friends and family.

Results:

n/a

Conclusions:

The BTS implemented in MYB is focused on maximising adherence and engagement with CCT over the short and long term in the setting of a fully digital trial that if successful could be delivered economically at scale. Clinical Trial: Maintain Your Brain Trial (ACTRN12618000851268)