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Using Community-Based Participatory Research to Co-Develop Hypotheses and Patient-Centered Outcomes Addressing Implementation Gaps in the Prevention of Acute Kidney Injury
ABSTRACT
Background:
Acute kidney injury (AKI) is a common renal impairment associated with diagnostic and interventional catheterization procedures. About 14% of all patients undergoing such procedures and about 50% of patients with pre-existing chronic kidney disease could develop AKI. Evidence-based interventions (EBIs) to prevent acute kidney injury are well-researched, considered standard of care, and endorsed by US and international nephrology and cardiovascular professional organizations. Despite established EBIs, they are inconsistently applied in clinical practice.
Objective:
This study utilized community-based participatory research to identify research questions, hypotheses, and patient-centered outcomes to improve uptake and maintenance of AKI EBIs in real-world clinical settings.
Methods:
In total, four patients and eight clinicians/scientists attended a one-hour virtual event to rank implementation models on best practices, real-world needs of patients, accessibility, and effectiveness.
Results:
Two implementation models emerged that met all criteria: Collaborative with Surveillance vs. Technical Assistance (standard of care).
Conclusions:
Choosing between these models presented a decisional dilemma, and this study provides the groundwork for a comparative effectiveness study.
Citation
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Copyright
© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.