Previously submitted to: JMIR Cancer (no longer under consideration since Dec 03, 2024)
Date Submitted: Jul 18, 2024
Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.
Recent developments in photothermal therapy: A bibliometric and visual analysis
ABSTRACT
Background:
Photothermal therapy (PTT) has recently garnered significant attention as a prominent noninvasive treatment modality for a broad spectrum of diseases. Despite the increasing volume of scholarly output over the last 20 years, a holistic synthesis delineating worldwide research trajectories remains elusive.
Objective:
We undertook a bibliometric analysis of the literature spanning 2004 to 2023 aiming to delineate the prevailing focal points and illuminate prospective research avenues.
Methods:
Research articles on PTT were retrieved from the Web of Science Core Collection database. Using tools such as CiteSpace, VOSviewer, and Bibliometrix, we performed a comprehensive analysis and visualization of annual publication trends, favored academic journals, global collaborative networks, co-cited references, and prevalent keywords.
Results:
Over the past 20 years, 11,184 academic papers on PTT have been published. Among the contributing countries, China had the highest number of publications, accounting for 70.1% of the total number of research papers, with the top 10 publishing institutions also being from China. Journals related to PTT primarily comprised interdisciplinary and comprehensive journals. Research related to PTT has primarily focused on its antitumor properties. Based on keyword search analysis, we concluded that “chemodynamic therapy,” “nanozyme,” “immunogenic cell death,” and “antimicrobial” reflected the current research hotspots.
Conclusions:
Medical applications of PTT have garnered considerable attention, with notable contributions emerging from Chinese research institutions. Current focal areas in this domain include the synergistic combination of PTT with photodynamic therapy, the immunological mechanisms of PTT to enhance its therapeutic efficacy, the integrated use of PTT with nanoenzyme catalysis, and the role of PTT in antimicrobial applications. This bibliometric analysis serves as a pioneering effort that examines the medical applications of PTT, offering insights into the global research landscape, key areas of interest, and emerging trends, thereby providing a valuable reference for future studies in this field.
Citation
The author of this paper has made a PDF available, but requires the user to login, or create an account.
Copyright
© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.