Previously submitted to: JMIR Public Health and Surveillance (no longer under consideration since Mar 05, 2024)
Date Submitted: Nov 24, 2023
Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.
Association between comprehensive dietary antioxidant index and metabolic syndrome and its components: findings from the 2003–2018 NHANES data
ABSTRACT
Background:
The relationship between Composite Dietary Antioxidant Index (CDAI) and metabolic syndrome (MetS) remains unclear.
Objective:
This study used data from the NHANES database on 5,493 participants aged 60 years or above from 2003 to 2018 to assess the relationship between CDAI and MetS.
Methods:
MetS are defined based on criteria proposed by the third report of the National Cholesterol Education Program Adult Group. The scoring method established by Wright was adjusted to calculate CDAI. We divided CDAI scores into 4 quantiles and analyzed the relationship between CDAI and MetS using multiple logistic regression and restricted cubic spline.
Results:
Our findings showed that CDAI was inversely associated with MetS and significantly affected waist circumference, blood pressure, and triglyceride levels. The highest quartile of CDAI and the multi-factor adjusted OR values and 95% confidence interval (CI) of MetS, waist circumference, blood pressure and triglycerides were 0.97 (0.94-0.99), 0.96 (0.93-1.00), 0.97 (0.95-0.99), 0.95 (0.93-0.98), respectively. In addition, subgroup analyses showed that female with high CDAI scores were less prone to develop MetS, obesity, and hypertension than male.
Conclusions:
Our cross-sectional study highlighted that dietary antioxidant intake is strongly associated with MetS. Further research needs to be conducted to confirm this consequence.
Citation
Request queued. Please wait while the file is being generated. It may take some time.
Copyright
© The authors. All rights reserved. This is a privileged document currently under peer-review/community review (or an accepted/rejected manuscript). Authors have provided JMIR Publications with an exclusive license to publish this preprint on it's website for review and ahead-of-print citation purposes only. While the final peer-reviewed paper may be licensed under a cc-by license on publication, at this stage authors and publisher expressively prohibit redistribution of this draft paper other than for review purposes.