Previously submitted to: Journal of Medical Internet Research (no longer under consideration since Oct 28, 2022)
Date Submitted: Oct 4, 2022
Warning: This is an author submission that is not peer-reviewed or edited. Preprints - unless they show as "accepted" - should not be relied on to guide clinical practice or health-related behavior and should not be reported in news media as established information.
Primary adrenal anaplastic large cell lymphoma: a case report and literature review
ABSTRACT
Involvement of the adrenal gland by anaplastic large cell lymphoma (ALCL) is infrequent. We report a 69-year-old male patient who underwent general weakness and anorexia for one year. Positron emission tomography-computed tomography (PET-CT) scan demonstrated that an exophytic mass on bilateral adrenal gland. The pathological diagnosis was considered to be ALK-negative ALCL, which was extremely rare. The treatment effect of ring CHOP-E regimen was not satisfactory, and the patient's condition improved after recevied CD30 mab combined with CHP regimen. We review previously reported cases in the literature to better characterize this rare disease. ALCL is an extremely rare adrenal gland tumor with atypical clinical and imaging manifestations, and is easily misdiagnosed. A comprehensive model of chemotherapy and radiotherapy is recommended for treatment, but the prognosis is poor.
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